Many of the posts I've read in various places recommended The Fly Lady for cleaning and organizing. I've gone to her website to peruse, but didn't like the layout nor was impressed with the content of the site. Still, determined to keep an open mind, I borrowed her book, Sink Reflections, from the library. I read it and came to the realization that her style really does not mesh with mine. If that's the case, there must be other souls who don't like her style either.
For those who want something different, I recommend several other resources: Get Organized Now, The Clean Team, and The Clean Report. The Clean Report was started by Don Aslett who has written many very readable, and humorous, tomes on the topic of cleaning, among which is Is There Life After Housework?
Of course, if you want a major overhaul of your life, simplifying it as a holistic process rather than just applying a quick fix or bandage, then I highly recommend The Simple Living Guide by Janet Luhrs and, to some extent, her website Simple Living dot com. Another terrific resource is The Simple Living Network, spawned from the classic book Your Money or Your Life by Joe Dominguez and Vicki Robin.
"To be conscious that you are ignorant is a great step to knowledge." ~ Benjamin Disraeli (1804 - 1881)